Team Leader Rational Design
Ichnos Sciences
Competitive Salary

We are currently working on an exciting opportunity with a newly created, independent, fully integrated, global biotech company focused on innovation. They are looking for a knowledgeable scientist with experience in running an antibody rational design group to lead their scientists to design antibodies and bi/multispecific antibodies from inception to lead selection for industrialisation. This is a rare opportunity to lead a growing scientific team at the very start of something special. You will become a part of the foundation of a new company, making yourself an imprint…

Key Responsibilities:

- Establish a highly functioning rational design group.

- Lead the design, characterization and developability of bi/multispecific antibodies.

- Lead the development of innovative solutions to engineer and characterize antibodies and novel antibody formats.

- Lead Fc engineering projects.

- Guide scientists and team to address complex processes and transition leads for industrialization.

Key experience:

You will have substantial scientific knowledge and a practical experience in protein design, protein biophysical characterization and antibody developability assessment.

The company will heavily rely on your proven leadership skills in guiding and mentoring principal scientists, research officers, and associates learning along the way from vast accumulated in-house knowledge and thus making a significant impact.

Education & Desired Experience:

- Ph.D. in Molecular Biology, Biochemistry, Structural Biology or related fields with relevant industrial experience.

- Strong hands-on experience with making T cell and/or other immune cell engagers is preferred.

- Thorough knowledge and practical experience in protein engineering, protein expression, protein-protein interaction techniques, protein structure, and biophysical methods. Experience with Fc engineering is a plus.

- Demonstrated experience in managing research technicians and PhD scientists.

- Demonstrated experience with bioinformatics and 3D antibody modelling techniques.

- Good understanding of the Biologics Drug Discovery process from idea to IND and beyond.

For an informal and confidential discussion, please speak with our advisors at Berwick Partners:

Caroline Hunt

Consultant, Life Sciences Practice

+ 44 (0)161 498 3424

Closing date: 3rd January 2020

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